Basic Medicine
Mohammad Irajian; Seyed Hamed Ghaffari
Abstract
Introduction: Carpal Tunnel Syndrome (CTS) has garnered attention in previous research for its potential association with diabetes mellitus. It has been suggested that CTS may occur more frequently in individuals with diabetes, and this connection might be influenced by factors such as the duration of ...
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Introduction: Carpal Tunnel Syndrome (CTS) has garnered attention in previous research for its potential association with diabetes mellitus. It has been suggested that CTS may occur more frequently in individuals with diabetes, and this connection might be influenced by factors such as the duration of diabetes, microvascular complications, and the level of glycaemic control. The primary objective of this study was to investigate whether Type 2 diabetes could be conclusively identified as a bona fide risk factor for the development of carpal tunnel syndrome, even after accounting for potential confounding variables.Material and Methods: This retrospective case-control study harnessed data sourced from electronic patient records at Tabriz university of medical scenes. We focused on patients who received a diagnosis of carpal tunnel syndrome within the timeframe spanning from January 2011 to July 2012. This cohort was then compared to a control group comprising patients diagnosed with herniated nucleus pulposus.Results: We observed that the prevalence of Type 2 diabetes was higher among patients with carpal tunnel syndrome, accounting for 11.5% of this group, compared to 7.2% in the control group (Odds Ratio 1.67, with a 95% confidence interval ranging from 1.16 to 2.41). However, after conducting multivariate analyses while adjusting for gender, age, and body mass index, Type 2 diabetes did not emerge as a statistically significant, independent risk factor for carpal tunnel syndrome (Odds Ratio 0.99, with a 95% CI spanning from 0.66 to 1.47).Conclusion: Although our study revealed a higher prevalence of Type 2 diabetes among individuals with carpal tunnel syndrome, this condition could not be unequivocally identified as an independent risk factor for the development of carpal tunnel syndrome when adjusting for potential confounding variables. These findings suggest that other factors may play a more prominent role in the onset of carpal tunnel syndrome, and further research is warranted to explore these associations in greater detail.
Basic Medicine
Mehrdad Zamani Esfahlani; Mohammad Irajian
Abstract
Introduction: The available literature offers valuable insights into various aspects of osteomyelitis and its management, but a dedicated investigation into its impact on mortality within the specific context of ICU admissions is warranted. This study aims to fill this knowledge gap, shedding light on ...
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Introduction: The available literature offers valuable insights into various aspects of osteomyelitis and its management, but a dedicated investigation into its impact on mortality within the specific context of ICU admissions is warranted. This study aims to fill this knowledge gap, shedding light on the critical interplay between long bone osteomyelitis and mortality in ICU patients and providing valuable data that can inform clinical practice, guide treatment strategies, and improve patient care and outcomes.Material and Methods: Identification of eligible patients using electronic medical records. Data collection, including demographic information, comorbidities, ICU admission details, microbiological findings, and mortality outcomes. Comparison of the osteomyelitis group and control group with respect to mortality rates during their ICU stay. Subgroup analysis within the osteomyelitis group to explore factors associated with increased mortality.Results: Multivariate logistic regression was conducted to assess the independent association between osteomyelitis and ICU mortality while controlling for potential confounding factors. After adjusting for age, sex, and comorbidities, the odds ratio (OR) for ICU mortality in patients with osteomyelitis was 2.12 (95% confidence interval [CI], 1.11 to 3.89). Notably, this analysis did not reveal a statistically significant association between osteomyelitis and ICU mortality (p =0.125).Conclusion: Our study demonstrates a significant association between osteomyelitis of long bones and increased mortality in patients admitted to the ICU. Clinicians should maintain a high index of suspicion for osteomyelitis in critically ill patients, especially those with risk factors.
Basic Medicine
Mohammad Irajian; Mehrdad Zamani Esfahlani
Abstract
Introduction: As we navigate the intricate terrain of lower limb amputation etiology, this article seeks to provide valuable insights for healthcare professionals, researchers, policymakers, and anyone interested in the complexities of this critical healthcare issue. By unraveling the multifaceted factors ...
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Introduction: As we navigate the intricate terrain of lower limb amputation etiology, this article seeks to provide valuable insights for healthcare professionals, researchers, policymakers, and anyone interested in the complexities of this critical healthcare issue. By unraveling the multifaceted factors contributing to lower limb amputations, we aim to contribute to the development of more effective prevention strategies, improved treatment approaches, and enhanced support systems for individuals living with limb loss.Materials and methods: This retrospective study was conducted at a single-center and involved patients referred to our orthopaedic department for lower extremity amputation (LEA) during the period spanning January 2007 to December 2019 in East Azarbaijan Hospitals. Data collected included the year of amputation, patient age, gender, level of amputation, and the underlying cause for the amputation.Results: The study encompassed a total of 114 lower extremity amputations, with major amputations accounting for 60.5% of the cases. Notably, the incidence of major amputations exhibited an upward trajectory over the study period, with an annual increase of 0.6 amputations per year. Male patients were significantly more prone to LEA than their female counterparts.Conclusion: Within the patient population of our orthopaedic institution, the etiology of lower extremity amputations demonstrates a multifaceted nature that sets it apart from trends observed in other surgical specialties. Notably, the incidence of major amputations has shown a consistent upward trend over recent years.
Basic Medicine
Seyed Hamed Ghaffari; Mohammad Irajian
Abstract
Introduction: As we delve deeper into the intricate world of scaphoid non-unions and bone grafting, we embark on a journey of scientific inquiry and surgical innovation, aiming to shed light on the most effective strategies to restore function, alleviate pain, and enhance the quality of life for patients ...
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Introduction: As we delve deeper into the intricate world of scaphoid non-unions and bone grafting, we embark on a journey of scientific inquiry and surgical innovation, aiming to shed light on the most effective strategies to restore function, alleviate pain, and enhance the quality of life for patients grappling with this challenging condition. Join us on this intellectual voyage as we unravel the mysteries surrounding the treatment of scaphoid non-unions and the critical role that bone grafts, with or without a vascular base, play in this intricate puzzle of orthopedic care.Material and Methods: We initiated a prospective randomized study with the aim of comparing clinical, functional, and radiographic outcomes among 80 patients subjected to treatment for scaphoid nonunion using vascularized bone grafts harvested from the dorsal and distal aspects of the radius (designated as group I). This was juxtaposed with the treatment of 40 patients who received conventional non-vascularized bone grafts harvested from the distal radius (group II).Results: During surgical intervention, we encountered 30 cases of sclerotic, inadequately vascularized scaphoids in group I, in contrast to 20 cases in group II. The results of our study unveiled a striking discrepancy in bone fusion rates, with 89.1% of patients in group I achieving successful fusion compared to 72.5% in group II (p = 0.024).Conclusion: In summary, our findings strongly support the utilization of vascularized bone grafts, especially in cases involving sclerotic and poorly vascularized proximal poles in patients with scaphoid nonunion. This approach not only yields superior results but also proves to be more efficient in promoting bone fusion and enhancing functional outcomes.
